Nikhef, the National Institute for Subatomic Physics is an institute that carries out research in the area of (astro)particle physics. Scientists and engineers work together on research into the smallest building blocks of matter and the forces that act between them. These miniscule particles are studied in collision processes using large particle accelerators, including those of CERN near Geneva, as well as in interactions of high-energy cosmic particles in the Earth's atmosphere or in seawater.

Nikhef is a partnership between the Foundation for Fundamental Research on Matter (FOM) and four universities: Radboud University Nijmegen, University of Amsterdam, Utrecht University and VU University Amsterdam. SURFsara is a partner of Nikhef.